Article
The cephalochordate amphioxus: a key to reveal the secrets of nuclear receptor evolution.
Briefings in functional genomics - 1 Mar 2012
Lecroisey Claire, Laudet Vincent, Schubert Michael
Abstract excerpt
The members of the nuclear receptor (NR) superfamily are transcription factors characterized by a particular mode of function, which is related to the conserved nature of their molecular structure. NR proteins usually contain a DNA-binding domain (DBD) and a ligand-binding domain (LBD) allowing them to directly bind to DNA and regulate target gene expression in a ligand-dependent manner. In this review, we are...
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