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Article

Mechanisms of quinolone resistance in clinical strains of Pseudomonas aeruginosa.

Microbial drug resistance (Larchmont, N.Y.) - 1 Jan 1998

Jalal S, Wretlind B

Abstract excerpt

Principal mechanisms of bacterial resistance to quinolones are modification of target enzymes, DNA gyrase (gyrA) and topoisomerase IV (parC), or reduction of intracellular concentration due to mutations in the regulatory genes for efflux systems, such as mexR and nfxB. We have examined gyrA, parC, mexR, and nfxB genes from 16 quinolone-resistant clinical isolates of Pseudomonas aeruginosa to determine the...

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Identifiers

PMID: 9988043
DOI: 10.1089/mdr.1998.4.257

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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