nfxC-type quinolone resistance in a clinical isolate of Pseudomonas aeruginosa

doi:10.1128/aac.39.3.790

Article

nfxC-type quinolone resistance in a clinical isolate of Pseudomonas aeruginosa

1 Mar 1995

Abstract excerpt

Quinolone resistance gene nqr-T91 in a clinical isolate of Pseudomonas aeruginosa P1481 was cotransducible with catA1 in P. aeruginosa PAO. The nqr-T91 transductant, PKH-T91, was resistant to norfloxacin, imipenem, and chloramphenicol and showed less norfloxacin accumulation than the parent strain did. Loss of the 46-kDa outer membrane protein (D2) and an increase in the 50-kDa outer membrane protein in PKH-T91...

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