Article
Mutant p53 protein is expressed in Bowen's disease.
The American Journal of dermatopathology - 1 Jun 1992
Sim C S, Slater S D, McKee P H
Abstract excerpt
A total of 26 specimens of histologically determined, cutaneous Bowen's disease from 23 patients were investigated for the incidence of mutant p53 protein expression by an indirect immunoperoxidase technique using the monoclonal antiserum CM1 on paraffin-embedded formalin-fixed tissue sections. Its potential role as a label of cutaneous malignancy was also evaluated: 15 specimens (57.7%) showed nuclear positivity...
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