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Article

Aberrant expression of p53 tumour-suppressor protein in non-melanoma skin cancer.

The British journal of dermatology - 1 Nov 1992

McGregor J M, Yu C C, Dublin E A, Levison D A, MacDonald D M

Abstract excerpt

Expression of the cellular p53 tumour-suppressor protein was examined in 78 epidermal tumours, including basal and squamous cell carcinomas, keratoacanthomas, solar keratoses, Bowen's disease and viral warts. An immunohistochemical study was employed using the antibody CM-1, raised against recombinant human p53 protein. Positive staining for p53, not detectable in normal cells because wild-type p53 is rapidly...

Topics

Bowen's Disease
Carcinoma, Basal Cell
Carcinoma, Squamous Cell
Genes, p53
Humans
Keratoacanthoma
Keratosis
Mutation
Skin
Skin Neoplasms
Tumor Suppressor Protein p53

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Warts

Source

Identifiers

PMID: 1467284
DOI: 10.1111/j.1365-2133.1992.tb14841.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1467284-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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