Relation of p53 tumor suppressor protein expression to human papillomavirus (HPV) DNA and to cellular atypia in male genital warts and in premalignant lesions.

doi:10.2340/0001555575180186

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Article

Relation of p53 tumor suppressor protein expression to human papillomavirus (HPV) DNA and to cellular atypia in male genital warts and in premalignant lesions.

Acta dermato-venereologica - 1 May 1995

Ranki A, Lassus J, Niemi K M

Abstract excerpt

Functional disturbance of p53 tumor suppressor protein contributes to uncontrolled cell growth. Human papillomavirus (HPV) E6 oncoproteins bind to wild-type p53 and abrogate its function. Our objective was to elucidate the relation of aberrant p53 protein expression to HPV DNA and cellular atypia in male genital warts and premalignant lesions. Immunohistochemically detectable p53 protein expression was studied in...

Topics

Bowen's Disease
Carcinoma in Situ
Cell Nucleus
Condylomata Acuminata
Cytoplasm
DNA, Viral
Disease Progression
Follow-Up Studies
Gene Expression Regulation, Viral
Humans
Immunohistochemistry

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Keratinocytes

Male

Mutation

Papillomaviridae

Papillomavirus Infections

Penile Diseases

Penile Neoplasms

Source

Open in PubMed

Identifiers

PMID: 7653176
DOI: 10.2340/0001555575180186

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7653176-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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