Article
Mutant p53 expression in solar keratosis: an immunohistochemical study.
Journal of cutaneous pathology - 1 Aug 1992
Sim C S, Slater S, McKee P H
Abstract excerpt
Thirty-eight solar keratoses from 32 patients were studied for expression of mutant p53 protein by an immunohistochemical technique. Twenty-eight of the 38 solar keratoses (73.7%) showed positive and variable nuclear labelling, whereas 10 specimens were immunonegative. The nuclear immunopositivity which was seen in all variants was mostly diffuse in distribution. The adjacent "normal" epidermis of 8 keratoses...
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