Mutant p53 expression in solar keratosis: an immunohistochemical study.

doi:10.1111/j.1600-0560.1992.tb01366.x

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Article

Mutant p53 expression in solar keratosis: an immunohistochemical study.

Journal of cutaneous pathology - 1 Aug 1992

Sim C S, Slater S, McKee P H

Abstract excerpt

Thirty-eight solar keratoses from 32 patients were studied for expression of mutant p53 protein by an immunohistochemical technique. Twenty-eight of the 38 solar keratoses (73.7%) showed positive and variable nuclear labelling, whereas 10 specimens were immunonegative. The nuclear immunopositivit...

Topics

Aged
Biomarkers, Tumor
Carcinoma, Squamous Cell
Female
Genes, p53
Humans
Immunohistochemistry
Keratosis
Male
Mutation
Skin
Skin Neoplasms
Sunlight
Tumor Suppressor Protein p53

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