Low frequency of p53 gene mutation and protein expression in mucinous colorectal carcinomas.

doi:10.1016/0304-3835(96)04208-5

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Article

Low frequency of p53 gene mutation and protein expression in mucinous colorectal carcinomas.

Cancer letters - 5 Jun 1996

Hanski C, Tiecke F, Hummel M, Hanski M L, Ogorek D, Rolfs A, Schmitt-Gräff A, Stein H, Riecken E O

Abstract excerpt

Immunohistochemical data indicate that the frequency of p53 protein overexpression is consistently lower in the mucinous than in the non-mucinous carcinomas of the breast, ovary, pancreas and colon. This peculiar immunohistochemical behavior of the mucinous phenotype could be due to the effect of...

Topics

Adenocarcinoma, Mucinous
Base Sequence
Colorectal Neoplasms
DNA Primers
Genes, p53
Humans
Immunoenzyme Techniques
Molecular Sequence Data
Mutation
Point Mutation
Tumor Suppressor Protein p53

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