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Article

Recombinogenic phenotype of human activation-induced cytosine deaminase.

Journal of immunology (Baltimore, Md. : 1950) - 1 Apr 2004

Poltoratsky Vladimir P, Wilson Samuel H, Kunkel Thomas A, Pavlov Youri I

Abstract excerpt

Class switch recombination, gene conversion, and somatic hypermutation that diversify rearranged Ig genes to produce various classes of high affinity Abs are dependent on the enzyme activation-induced cytosine deaminase (AID). Evidence suggests that somatic hypermutation is due to error-prone DNA...

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Share to AICDA (Activation-Induced Cytidine Deaminase)
Share to Base Pair Mismatch
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Somatic Hypermutation, Immunoglobulin

Source

Identifiers

PMID: 15034045
DOI: 10.4049/jimmunol.172.7.4308

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15034045-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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