Article
Activation-induced cytidine deaminase structure and functions: a species comparative view.
Developmental and comparative immunology - 1 Sept 2011
Barreto Vasco M, Magor Brad G
Abstract excerpt
In the ten years since the discovery of activation-induced cytidine deaminase (AID) there has been considerable effort to understand the mechanisms behind this enzyme's ability to target and modify immunoglobulin genes leading to somatic hypermutation and class switch recombination. While the majority of research has focused on mouse and human models of AID function, work on other species, from lamprey to rabbit...
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