Article
Saccharomyces cerevisiae as a model system to study the response to anticancer agents.
Cancer chemotherapy and pharmacology - 1 Oct 2012
Matuo Renata, Sousa Fabrício G, Soares Daniele G, Bonatto Diego, Saffi Jenifer, Escargueil Alexandre E, Larsen Annette K, Henriques João Antonio Pêgas
Abstract excerpt
The development of new strategies for cancer therapeutics is indispensable for the improvement of standard protocols and the creation of other possibilities in cancer treatment. Yeast models have been employed to study numerous molecular aspects directly related to cancer development, as well as to determine the genetic contexts associated with anticancer drug sensitivity or resistance. The budding yeast...
Topics
- Antineoplastic Agents
- Cell Cycle
- DNA Repair
- Drug Resistance
- Epigenesis, Genetic
- Humans
- Mutation
- Saccharomyces cerevisiae