Article
Low frequency and late occurrence of p53 and dcc aberrations in colorectal tumours.
Journal of cancer research and clinical oncology - 1 Jan 1995
Froggatt N J, Leveson S H, Garner R C
Abstract excerpt
Whilst p53 aberrations have been documented in numerous malignancies, reports of alterations to the deleted in colorectal cancer (dcc) gene are infrequent, and studies investigating the status of both genes in the same colon tumour are rare. In this study we have analysed a panel of 35 pairs of normal and neoplastic human colorectal tissues for abnormalities in these tumour-suppressor genes. In contrast to...
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