Low frequency and late occurrence of p53 and dcc aberrations in colorectal tumours.

doi:10.1007/BF01202723

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Article

Low frequency and late occurrence of p53 and dcc aberrations in colorectal tumours.

Journal of cancer research and clinical oncology - 1 Jan 1995

Froggatt N J, Leveson S H, Garner R C

Abstract excerpt

Whilst p53 aberrations have been documented in numerous malignancies, reports of alterations to the deleted in colorectal cancer (dcc) gene are infrequent, and studies investigating the status of both genes in the same colon tumour are rare. In this study we have analysed a panel of 35 pairs of n...

Topics

Adult
Aged
Aged, 80 and over
Base Sequence
Chromosomes, Human, Pair 18
Colorectal Neoplasms
DNA, Neoplasm
DNA, Satellite
Female
Gene Deletion
Genes, DCC
Genes, p53
Genetic Carrier Screening
Humans
Male
Middle Aged
Molecular Sequence Data
Mutation

Source

Open in PubMed

Identifiers

PMID: 7860623
DOI: 10.1007/BF01202723

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7860623-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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