Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The DCC Protein and Prognosis in Colorectal Cancer

5 Dec 1996

Abstract excerpt

BACKGROUND: Allelic loss of chromosome 18q predicts a poor outcome in patients with stage II colorectal cancer. Although the specific gene inactivated by this allelic loss has not been elucidated, the DCC (deleted in colorectal cancer) gene is a candidate. We investigated whether the expression of the DCC protein in tumor cells is a prognostic marker in colorectal carcinoma. METHODS: The expression of DCC was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Genetic factors in colorectal cancer
Share to Wnt/β-catenin signaling in development and cancer

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 8929264
DOI: 10.1056/nejm199612053352303

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The DCC Protein and Prognosis in Colorectal CancerPMID 8929264Read ↗

Prognostic significance of allelic lost at chromosome 18q21 for stage II colorectal cancer.Semantic proximity Read ↗

Identification of a chromosome 18q gene that is altered in colorectal cancers.Semantic proximity Read ↗

Role of the Dependence Receptor DCC in Colorectal Cancer PathogenesisSemantic proximity Read ↗

The DCC gene: structural analysis and mutations in colorectal carcinomas.Semantic proximity Read ↗

Altered phenotype of HT29 colonic adenocarcinoma cells following expression of the DCC gene.Semantic proximity Read ↗

Clinical significance of p53, K-ras and DCC gene alterations in the stage I-II colorectal cancers.Semantic proximity Read ↗

Loss of DCC gene expression is of prognostic importance in acute myelogenous leukemia.Semantic proximity Read ↗

DCC expression is altered by multiple mechanisms in brain tumours.Semantic proximity Read ↗

The 18q21 region in colorectal and pancreatic cancer: independent loss of DCC and DPC4 expression.Semantic proximity Read ↗

[Structure and function of DCC (deleted in colorectal cancer) gene and its product].Semantic proximity Read ↗

Allelic loss of chromosome 18q and prognosis in colorectal cancer.Semantic proximity Read ↗

Frequent allelic deletions and loss of expression characterize the DCC gene in male germ cell tumors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.