Article
Phosphorylation of histone H2A inhibits transcription on chromatin templates.
The Journal of biological chemistry - 21 May 2004
Zhang Ye, Griffin Karen, Mondal Neelima, Parvin Jeffrey D
Abstract excerpt
The regulation of gene expression via the histone code has, for the most part, revealed that histone modifications cause the recruitment of adaptor proteins that indirectly regulate the synthesis of RNA. Using purified factors to assemble and modify the chromatin and to transcribe the DNA, we investigated whether modifications of histones may directly impact the RNA polymerase II transcription process. We...
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