Article
A genetic analysis reveals novel histone residues required for transcriptional reprogramming upon stress.
Nucleic acids research - 17 Apr 2020
Viéitez Cristina, Martínez-Cebrián Gerard, Solé Carme, Böttcher René, Potel Clement M, Savitski Mikhail M, Onnebo Sara, Fabregat Marc, Shilatifard Ali, Posas Francesc, de Nadal Eulàlia
Abstract excerpt
Cells have the ability to sense, respond and adapt to environmental fluctuations. Stress causes a massive reorganization of the transcriptional program. Many examples of histone post-translational modifications (PTMs) have been associated with transcriptional activation or repression under steady-state growth conditions. Comparatively less is known about the role of histone PTMs in the cellular adaptive response...
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