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Article

Histone deacetylase 1 phosphorylation promotes enzymatic activity and complex formation.

The Journal of biological chemistry - 14 Dec 2001

Pflum M K, Tong J K, Lane W S, Schreiber S L

Abstract excerpt

Accessibility of the genome to DNA-binding transcription factors is regulated by proteins that control the acetylation of amino-terminal lysine residues on nucleosomal histones. Specifically, histone deacetylase (HDAC) proteins repress transcription by deacetylating histones. To date, the only known regulatory mechanism of HDAC1 function is via interaction with associated proteins. Although the control of HDAC1...

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Source

Identifiers

PMID: 11602581
DOI: 10.1074/jbc.M105590200

Genes

HDAC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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