Article
The acetyltransferase HAT1 moderates the NF-κB response by regulating the transcription factor PLZF.
Nature communications - 13 Apr 2015
Sadler Anthony J, Suliman Bandar A, Yu Liang, Yuan Xiangliang, Wang Die, Irving Aaron T, Sarvestani Soroush T, Banerjee Ashish, Mansell Ashley S, Liu Jun-Ping, Gerondakis Steve, Williams Bryan R G, Xu Dakang
Abstract excerpt
To date, the activities of protein kinases have formed the core of our understanding of cell signal transduction. Comprehension of the extent of protein acetylation has raised expectations that this alternate post-transcriptional modification will be shown to rival phosphorylation in its importance in mediating cellular responses. However, limited instances have been identified. Here we show that signalling from...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.