Article
Clinical and therapeutic implications of hepatitis C virus compartmentalization.
Gastroenterology - 1 Jul 2006
Di Liberto Gaëtana, Roque-Afonso Anne-Marie, Kara Rachid, Ducoulombier Delphine, Fallot Guillaume, Samuel Didier, Feray Cyrille
Abstract excerpt
BACKGROUND & AIMS: Blood mononuclear cells (BMCs) frequently are infected by hepatitis C virus (HCV) variants that are not found in plasma. The influence of this compartmentalization on the natural and therapeutic outcome of hepatitis C is unknown. METHODS: We studied 119 patients with previously untreated chronic HCV infection. Sixty-five of these patients started first-line treatment with pegylated...
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