Article
Hepatitis C virus molecular evolution: transmission, disease progression and antiviral therapy.
World journal of gastroenterology - 21 Nov 2014
Preciado Maria Victoria, Valva Pamela, Escobar-Gutierrez Alejandro, Rahal Paula, Ruiz-Tovar Karina, Yamasaki Lilian, Vazquez-Chacon Carlos, Martinez-Guarneros Armando, Carpio-Pedroza Juan Carlos, Fonseca-Coronado Salvador, Cruz-Rivera Mayra
Abstract excerpt
Hepatitis C virus (HCV) infection represents an important public health problem worldwide. Reduction of HCV morbidity and mortality is a current challenge owned to several viral and host factors. Virus molecular evolution plays an important role in HCV transmission, disease progression and therapy outcome. The high degree of genetic heterogeneity characteristic of HCV is a key element for the rapid adaptation of...
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