Article
Genetic characterization of hepatitis B virus in peripheral blood leukocytes: evidence for selection and compartmentalization of viral variants with the immune escape G145R mutation.
Journal of virology - 1 Oct 2009
Datta Sibnarayan, Panigrahi Rajesh, Biswas Avik, Chandra Partha K, Banerjee Arup, Mahapatra Pradip K, Panda Chinmoy K, Chakrabarti Shekhar, Bhattacharya Sujit K, Biswas Kuntal, Chakravarty Runu
Abstract excerpt
The compartmentalization of viral variants in distinct host tissues is a frequent event in many viral infections. Although hepatitis B virus (HBV) classically is considered hepatotropic, it has strong lymphotropic properties as well. However, unlike other viruses, molecular evolutionary studies to characterize HBV variants in compartments other than hepatocytes or sera have not been performed. The present work...
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