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Article

Six novel UDP-glucuronosyltransferase (UGT1A3) polymorphisms with varying activity.

Journal of human genetics - 1 Jan 2004

Iwai Masaru, Maruo Yoshihiro, Ito Masaki, Yamamoto Kazuo, Sato Hiroshi, Takeuchi Yoshihiro

Abstract excerpt

Human UDP-glucuronosyltransferase (UGT) is a part of a major excretion pathway for endobiotics and xenobiotics. The UGT family of genes is highly polymorphic, and our aim is to describe novel polymorphisms at the UGT1A3 locus and determine how they alter substrate metabolism and drug reactions. One hundred healthy Japanese adults volunteered for the present study. We sequenced PCR-amplified fragments of the gene...

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Identifiers

PMID: 14986168
DOI: 10.1007/s10038-003-0119-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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