Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Variation of hepatic glucuronidation: Novel functional polymorphisms of the UDP-glucuronosyltransferase UGT1A4.

Hepatology (Baltimore, Md.) - 1 Apr 2004

Ehmer Ursula, Vogel Arndt, Schütte Jan Karl, Krone Britta, Manns Michael P, Strassburg Christian P

Abstract excerpt

UDP-glucuronosyltransferases are a family of drug metabolizing enzymes contributing to hepatic drug metabolism and protection against environmental toxins. The aim of this study was to identify polymorphisms at the human UGT1A gene locus and to characterize their function and potential associatio...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amines
Share to Carcinoma, Hepatocellular
Share to Catalysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glucuronic Acid

Share to Glucuronosyltransferase

Share to Luminescent Proteins

Share to Steroids

Share to Xenobiotics

Source

Identifiers

PMID: 15057901
DOI: 10.1002/hep.20131

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15057901-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Variation of hepatic glucuronidation: Novel functional polymorphisms of the UDP-glucuronosyltransferase UGT1A4.PMID 15057901Read ↗

Identification and functional characterization of UDP-glucuronosyltransferases UGT1A8*1, UGT1A8*2 and UGT1A8*3.Semantic proximity Read ↗

Family 1 uridine-5'-diphosphate glucuronosyltransferases (UGT1A): from Gilbert's syndrome to genetic organization and variability.Semantic proximity Read ↗

UGT pharmacogenomics: implications for cancer risk and cancer therapeutics.Semantic proximity Read ↗

Polymorphism of UDP-Glucuronosyltransferase and Drug MetabolismSemantic proximity Read ↗

UGT pharmacogenomicsSemantic proximity Read ↗

Polymorphisms in UDP glucuronosyltransferase genes: functional consequences and clinical relevance.Semantic proximity Read ↗

Variability and function of family 1 uridine-5'-diphosphate glucuronosyltransferases (UGT1A).Semantic proximity Read ↗

The Impact of UGT1A1 Genetic Variability on Enzyme Expression in Liver Pathology.Semantic proximity Read ↗

Genetic variability, haplotypes, and htSNPs for exons 1 at the human UGT1A locus.Semantic proximity Read ↗

UDP glucuronosyltransferase (UGT) 1A6 pharmacogenetics: I. Identification of polymorphisms in the 5'-regulatory and exon 1 regions, and association with human liver UGT1A6 gene expression and glucuronidation.Semantic proximity Read ↗

UGT genomic diversity: beyond gene duplication.Semantic proximity Read ↗

Genetic factors affecting gene transcription and catalytic activity of UDP-glucuronosyltransferases in human liver.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.