Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphism of UDP-Glucuronosyltransferase and Drug Metabolism

1 Apr 2005

Abstract excerpt

UDP-glucuronosyltransferase is a group of catabolic enzymes involved in the detoxification and excretion of many xenobiotic and endogeneous substances in intrahepatic and extrahepatic tissues. The group consists of two subfamilies, UGT1 and UGT2. UGT1 consists of 5 exons and has a unique gene structure. There are thirteen exon 1s from UGT1A1 to UGT1A13P, and exon 2 to exon 5 are used in common for all mRNAs...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Pharmacogenetics and Drug Metabolism
Share to Diet, Metabolism, and Disease
Share to Metabolism, Diabetes, and Cancer

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15853761
DOI: 10.2174/1389200053586064

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphism of UDP-Glucuronosyltransferase and Drug MetabolismPMID 15853761Read ↗

Polymorphisms in UDP glucuronosyltransferase genes: functional consequences and clinical relevance.Semantic proximity Read ↗

UGT pharmacogenomicsSemantic proximity Read ↗

Family 1 uridine-5'-diphosphate glucuronosyltransferases (UGT1A): from Gilbert's syndrome to genetic organization and variability.Semantic proximity Read ↗

UGT pharmacogenomics: implications for cancer risk and cancer therapeutics.Semantic proximity Read ↗

Genetic variation of human UDP-glucuronosyltransferase: implications in disease and drug glucuronidation.Semantic proximity Read ↗

The relationship between UGT1A1 gene & various diseases and prevention strategiesSemantic proximity Read ↗

Variability and function of family 1 uridine-5'-diphosphate glucuronosyltransferases (UGT1A).Semantic proximity Read ↗

[Progress in the study of UDP-glucuronosyltransferase gene polymorphism].Semantic proximity Read ↗

Drug-mediated toxicity caused by genetic deficiency of UDP-glucuronosyltransferases.Semantic proximity Read ↗

[Review on gene polymorphisms of UDP-glucuronosyltransferases and genetic susceptibility of cancer].Semantic proximity Read ↗

Variation of hepatic glucuronidation: Novel functional polymorphisms of the UDP-glucuronosyltransferase UGT1A4.Semantic proximity Read ↗

Nomenclature update for the mammalian UDP glycosyltransferase (UGT) gene superfamilySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.