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Article

UGT genomic diversity: beyond gene duplication.

Drug metabolism reviews - 1 Feb 2010

Guillemette Chantal, Lévesque Eric, Harvey Mario, Bellemare Judith, Menard Vincent

Abstract excerpt

The human uridine diphospho (UDP)-glucuronosyltransferase (UGT) superfamily comprises enzymes responsible for a major biotransformation phase II pathway: the glucuronidation process. The UGT enzymes are located in the endoplasmic reticulum of almost all tissues, where they catalyze the inactivation of several endogenous and exogenous molecules, including bilirubin, sex steroids, numerous prescribed drugs, and...

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Identifiers

PMID: 19857043
DOI: 10.3109/03602530903210682

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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