Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

UGT pharmacogenomics: implications for cancer risk and cancer therapeutics.

Pharmacogenetics - 1 Aug 2003

Desai Apurva A, Innocenti Federico, Ratain Mark J

Abstract excerpt

UDP-glucuronosyltransferases (UGTs) belong to a superfamily of microsomal enzymes responsible for glucuronidation of numerous endogenous and exogenous compounds including bilirubin, hormones, various drugs as well as environmental carcinogens. Glucuronidation predominantly serves as a pathway for elimination of the different glucuronidated compounds. Seventeen human UGT transcripts have been identified thus far,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Variation
Share to Genome, Human
Share to Glucuronosyltransferase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Isoenzymes

Share to Neoplasms

Share to Pharmacogenetics

Share to Pharmacogenetics and Drug Metabolism

Share to RNA, Messenger

Source

Identifiers

PMID: 12893990
DOI: 10.1097/01.fpc.0000054116.14659.e5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

UGT pharmacogenomics: implications for cancer risk and cancer therapeutics.PMID 12893990Read ↗

UGT pharmacogenomicsSemantic proximity Read ↗

UGT genomic diversity: beyond gene duplication.Semantic proximity Read ↗

Genetic variation of human UDP-glucuronosyltransferase: implications in disease and drug glucuronidation.Semantic proximity Read ↗

Genetic polymorphisms of human UDP-glucuronosyltransferase (UGT) genes and cancer risk.Semantic proximity Read ↗

Emerging roles for UDP-glucuronosyltransferases in drug resistance and cancer progressionSemantic proximity Read ↗

Polymorphisms in UDP glucuronosyltransferase genes: functional consequences and clinical relevance.Semantic proximity Read ↗

Uridine diphosphoglucuronosyltransferase pharmacogenetics and cancer.Semantic proximity Read ↗

[Review on gene polymorphisms of UDP-glucuronosyltransferases and genetic susceptibility of cancer].Semantic proximity Read ↗

Polymorphism of UDP-Glucuronosyltransferase and Drug MetabolismSemantic proximity Read ↗

The Functionality of UDP-Glucuronosyltransferase Genetic Variants and their Association with Drug Responses and Human DiseasesSemantic proximity Read ↗

Nomenclature update for the mammalian UDP glycosyltransferase (UGT) gene superfamilySemantic proximity Read ↗

Family 1 uridine-5'-diphosphate glucuronosyltransferases (UGT1A): from Gilbert's syndrome to genetic organization and variability.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.