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Identification and functional characterization of UDP-glucuronosyltransferases UGT1A81, UGT1A82 and UGT1A8*3.

Pharmacogenetics - 1 Jun 2002

Huang Yue-Hua, Galijatovic Alema, Nguyen Nghia, Geske Donald, Beaton Deirdre, Green Judith, Green Mark, Peters Wilbert H, Tukey Robert H

Abstract excerpt

UDP-glucuronosyltransferase (UGT) 1A8 is part of the UGT1 locus and is expressed exclusively in extrahepatic tissues. Analysis of UGT1A8 exon 1 sequence has identified four genotypes from a population of 69 individuals. While there are four alleles, one of the single base pair changes leads to a silent mutation at T255, while the other mutations lead to amino acid substitutions at positions 173 and 277, creating...

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PMID: 12042666
DOI: 10.1097/00008571-200206000-00004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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