Article
Mitochondrial DNA mutation at the D310 (displacement loop) mononucleotide sequence in the pathogenesis of gallbladder carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Feb 2004
Tang Moying, Baez Sergio, Pruyas Martha, Diaz Alfonso, Calvo Alfonso, Riquelme Erick, Wistuba Ignacio I
Abstract excerpt
PURPOSE: Mutations in the mitochondrial DNA (mtDNA) have been observed frequently in human neoplasia, in both coding and noncoding regions. A mononucleotide repeat (poly-C) between 303 and 315 nucleotides (D310) within the regulatory displacement loop has been identified recently as a frequent ho...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
