Article
Mutational hotspots in the mitochondrial D-loop region of cancerous and precancerous colorectal lesions in Egyptian patients.
DNA and cell biology - 1 Nov 2011
Kassem Abdel Meguid, El-Guendy Nadia, Tantawy Marwa, Abdelhady Hala, El-Ghor Akmal, Abdel Wahab Abdel Hady
Abstract excerpt
Mutations in the mitochondrial genome (mtDNA) are associated with different types of cancer, specifically colorectal cancer (CRC). However, few studies have been performed on precancerous lesions, such as ulcerative colitis (UC) lesions and adenomatous polyps (AP). The aim of this study was to identify mtDNA mutations in the cancerous and precancerous lesions of Egyptian patients. An analysis of the mutations...
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