Article
Microsatellite instability in preneoplastic and neoplastic lesions of the gallbladder.
Journal of gastroenterology - 1 Jan 2005
Roa Juan Carlos, Roa Iván, Correa Pelayo, Vo Quynh, Araya Juan Carlos, Villaseca Miguel, Guzmán Pablo, Schneider Barbara G
Abstract excerpt
BACKGROUND: Gallbladder cancer is very common in Chile and is the leading cause of cancer deaths in women aged over 40 years. However, there is limited information about the molecular changes involved in its pathogenesis. Microsatellite analysis was performed using polymerase chain reaction (PCR)-based assays to identify genetic loci that were altered in neoplastic and preneoplastic conditions of early and...
Topics
- Adenocarcinoma
- Adult
- Age Factors
- Aged
- Aged, 80 and over
- Antibodies, Monoclonal
- Biomarkers, Tumor
- Chile
- Cholecystitis
- DNA-Binding Proteins
- Female
- Gallbladder Neoplasms
- Genetic Predisposition to Disease
- Genomic Instability