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Article

Analysis of mitochondrial DNA mutations in D-loop region in thyroid lesions.

Biochimica et biophysica acta - 1 Mar 2010

Ding Zhinan, Ji Jingzhang, Chen Guorong, Fang Hezhi, Yan Shihui, Shen Lijun, Wei Jia, Yang Kaiyan, Lu Jianxin, Bai Yidong

Abstract excerpt

BACKGROUND: Mitochondrial defects have been associated with various human conditions including cancers. METHODS: We analyzed the mutations at the mitochondrial DNA (mtDNA) in patients with different thyroid lesions. In particular, in order to investigate if the accumulation of mtDNA mutations play a role in tumor progression, we studied the highly variable main control region of mtDNA, the displacement-loop...

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Identifiers

PMID: 19463899
DOI: 10.1016/j.bbagen.2009.05.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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