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Article

Alterations in the mitochondrial displacement loop in lung cancers.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Nov 2003

Suzuki Makoto, Toyooka Shinichi, Miyajima Kuniharu, Iizasa Toshihiko, Fujisawa Takehiko, Bekele Nebiyou B, Gazdar Adi F

Abstract excerpt

PURPOSE: Alterations of the noncoding displacement (D) loop of mitochondrial DNA are present in many cancers. These alterations include numerical changes in a homopolymeric C tract (PCT) at positions 303-309 and single base substitutions (SBS). We determined the frequency of D-loop alterations in lung cancer cell lines and tumors, and related them to clinicopathologic features. EXPERIMENTAL DESIGN: We sequenced...

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PMID: 14654546

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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