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Article

Phenotypic characterization of mouse embryonic fibroblasts lacking heat shock factor 2.

Journal of cellular and molecular medicine - 1 Jan 2000

Paslaru Liliana, Morange M, Mezger Valérie

Abstract excerpt

In murine cells, the heat shock response is regulated by a transcription factor, HSF1, which triggers the transcription of heat shock genes. HSF2 has been shown to be involved in meiosis and mouse brain development. We characterized the effects of the absence of HSF2 in mouse embryonic fibroblasts (MEFs). The temperature threshold of the heat shock response appeared lowered in Hsf2(-/-) MEFS as monitored by the...

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Source

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Identifiers

PMID: 14754511
DOI: 10.1111/j.1582-4934.2003.tb00245.x
PMCID: PMC6740138

Genes

HSF1
HSF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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