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Article

Heat shock factor 2 is a stress‐responsive mediator of neuronal migration defects in models of fetal alcohol syndrome

15 Jul 2014

Abstract excerpt

Fetal alcohol spectrum disorder (FASD) is a frequent cause of mental retardation. However, the molecular mechanisms underlying brain development defects induced by maternal alcohol consumption during pregnancy are unclear. We used normal and Hsf2-deficient mice and cell systems to uncover a pivotal role for heat shock factor 2 (HSF2) in radial neuronal migration defects in the cortex, a hallmark of fetal alcohol...

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PMID: 25027850
DOI: 10.15252/emmm.201303311

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Heat shock factor 2 is a stress‐responsive mediator of neuronal migration defects in models of fetal alcohol syndromePMID 25027850Read ↗

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