Article
Multiple functions of Drosophila heat shock transcription factor in vivo.
The EMBO journal - 1 May 1997
Jedlicka P, Mortin M A, Wu C
Abstract excerpt
Heat shock transcription factor (HSF) is a transcriptional activator of heat shock protein (hsp) genes in eukaryotes. In order to elucidate the physiological functions of HSF in Drosophila, we have isolated lethal mutations in the hsf gene. Using a conditional allele, we show that HSF has an esse...
Topics
- Alleles
- Animals
- DNA-Binding Proteins
- Drosophila
- Drosophila Proteins
- Genes, Lethal
- Heat Shock Transcription Factors
- Hot Temperature
- Larva
- Male
- Mutation
- Oogenesis
- Phenotype