Article
HSF1 is required for extra-embryonic development, postnatal growth and protection during inflammatory responses in mice.
The EMBO journal - 1 Nov 1999
Xiao X, Zuo X, Davis A A, McMillan D R, Curry B B, Richardson J A, Benjamin I J
Abstract excerpt
HSF1 is the major heat shock transcriptional factor that binds heat shock element (HSE) in the promoter of heat shock proteins (Hsps) and controls rapid Hsp induction in cells subjected to various environmental stresses. Although at least four members of the vertebrate HSF family have been described, details of their individual physiological roles remain relatively obscure. To assess whether HSF1 exhibited...
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