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Article

S-phase checkpoint genes safeguard high-fidelity sister chromatid cohesion.

Molecular biology of the cell - 1 Apr 2004

Warren Cheryl D, Eckley D Mark, Lee Marina S, Hanna Joseph S, Hughes Adam, Peyser Brian, Jie Chunfa, Irizarry Rafael, Spencer Forrest A

Abstract excerpt

Cohesion establishment and maintenance are carried out by proteins that modify the activity of Cohesin, an essential complex that holds sister chromatids together. Constituents of the replication fork, such as the DNA polymerase alpha-binding protein Ctf4, contribute to cohesion in ways that are poorly understood. To identify additional cohesion components, we analyzed a ctf4Delta synthetic lethal screen...

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Share to Chromatids
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 14742710
DOI: 10.1091/mbc.e03-09-0637
PMCID: PMC379270

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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