Article
Identification of protein complexes required for efficient sister chromatid cohesion.
Molecular biology of the cell - 1 Apr 2004
Mayer Melanie L, Pot Isabelle, Chang Michael, Xu Hong, Aneliunas Victoria, Kwok Teresa, Newitt Rick, Aebersold Ruedi, Boone Charles, Brown Grant W, Hieter Philip
Abstract excerpt
Ctf8p is a component of Ctf18-RFC, an alternative replication factor C-like complex required for efficient sister chromatid cohesion in Saccharomyces cerevisiae. We performed synthetic genetic array (SGA) analysis with a ctf8 deletion strain as a primary screen to identify other nonessential genes required for efficient sister chromatid cohesion. We then assessed proficiency of cohesion at three chromosomal loci...
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