Article
A permissive retinoid X receptor/thyroid hormone receptor heterodimer allows stimulation of prolactin gene transcription by thyroid hormone and 9-cis-retinoic acid.
Molecular and cellular biology - 1 Jan 2004
Castillo Ana I, Sánchez-Martínez Ruth, Moreno Jose L, Martínez-Iglesias Olaia A, Palacios Daniela, Aranda Ana
Abstract excerpt
Heterodimers of the retinoid X receptor (RXR) with the thyroid hormone receptor (TR) are considered to be nonpermissive. It is believed that within these complexes RXR acts as a "silent partner." We demonstrate here that a permissive heterodimer mediates stimulation of prolactin expression by the...
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