Article
Ephemerally expressed wild-type and mutant steroid hormone receptors are equally able to influence expression of transient or resident templates.
Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie - 1 Nov 1995
Schneider S, Brenz Verca S, Rusconi S
Abstract excerpt
We have tested transiently expressed mutant and chimeric glucocorticoid receptors (GR) for their ability to influence transcription of either a co-transfected or a stably integrated reporter gene. To the latter purpose we have generated a cell line harbouring 2 chromosomally anchored copies of th...
Topics
- Animals
- Chimera
- Gene Expression
- Genes, Reporter
- In Vitro Techniques
- Lac Operon
- Mammary Tumor Virus, Mouse
- Mice
- Mutation
- Receptors, Androgen
- Receptors, Glucocorticoid
- Receptors, Progesterone
- Transcriptional Activation