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Article

Retinoid X receptor is a nonsilent major contributor to vitamin D receptor-mediated transcriptional activation.

Molecular endocrinology (Baltimore, Md.) - 1 Nov 2003

Bettoun David J, Burris Thomas P, Houck Keith A, Buck Donald W, Stayrook Keith R, Khalifa Berket, Lu Jianfen, Chin William W, Nagpal Sunil

Abstract excerpt

The vitamin D receptor (VDR) belongs to the thyroid hormone/retinoid receptor subfamily of nuclear receptors and functions as a heterodimer with retinoid X receptor (RXR). The RXR-VDR heterodimer, in contrast to other members of the class II nuclear receptor subfamily, is nonpermissive where RXR does not bind its cognate ligand, and therefore its role in VDR-mediated transactivation by liganded RXR-VDR has not...

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Identifiers

PMID: 12893883
DOI: 10.1210/me.2003-0148

Genes

VDR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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