Thyroid hormone receptors repress estrogen receptor activation of a TRE.

doi:10.1210/mend-5-3-365

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Article

Thyroid hormone receptors repress estrogen receptor activation of a TRE.

Molecular endocrinology (Baltimore, Md.) - 1 Mar 1991

Graupner G, Zhang X K, Tzukerman M, Wills K, Hermann T, Pfahl M

Abstract excerpt

The identification of hormone response elements in the promoter regions of hormonally regulated genes has revealed a striking similarity between the estrogen response element (ERE) and a palindromic thyroid hormone response element (TRE) derived from the GH gene promoter. In addition, this TRE was described as a strong retinoic acid receptor response element for all three subtypes: alpha, beta, and gamma. We show...

Topics

Base Sequence
Carrier Proteins
Chloramphenicol O-Acetyltransferase
DNA
Drug Synergism
Gene Expression Regulation
Humans
Ligands
Molecular Sequence Data
Mutation
Promoter Regions, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, Estrogen

Receptors, Retinoic Acid

Receptors, Thyroid Hormone

Transcription, Genetic

Transfection

Tretinoin

Source

Open in PubMed

Identifiers

PMID: 1653892
DOI: 10.1210/mend-5-3-365

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1653892-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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