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Article

Thyroid hormone receptor homodimers can function as ligand-sensitive repressors.

Molecular endocrinology (Baltimore, Md.) - 1 May 1995

Piedrafita F J, Bendik I, Ortiz M A, Pfahl M

Abstract excerpt

Unlike the steroid hormone receptors that bind their response elements as homodimers, thyroid hormone receptor (TRs) as well as retinoic acid receptors and several other receptors have been shown to require heterodimerization with retinoid X receptors (RXR) for efficient binding to most response elements. In this article we have compared in detail TR DNA binding and its gene-regulatory characteristics in the...

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Identifiers

PMID: 7565804
DOI: 10.1210/mend.9.5.7565804

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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