Article
Functional characterization of a natural retinoic acid responsive element.
The EMBO journal - 1 Dec 1991
Vivanco Ruiz M M, Bugge T H, Hirschmann P, Stunnenberg H G
Abstract excerpt
Retinoic acid receptor (RAR) and thyroid hormone receptor (T3R) are thought to bind as dimers to a T3 responsive element (T3REpal) comprised of inverted repeats of the half-site motif GGTCA. However, a RA responsive element (beta RARE) was previously identified in the promoter of the RAR beta 2 gene which contains two direct repeats of the motif GTTCA spaced by a six nucleotide gap. We now demonstrate the ability...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
