Article
Mutation rates in the complex microsatellite MYCL1 and related simple repeats in cultured human cells.
Mutation research - 12 Jan 2004
Hatch Stephanie B, Farber Rosann A
Abstract excerpt
Microsatellite instability is a phenotype observed in tumors cells that have defects in DNA mismatch repair (MMR). Most markers used for detecting microsatellite instability are mono- and dinucleotide repeats, but one tetranucleotide repeat (MYCL1) has been reported to be useful for this purpose. The MYCL1 repeat is actually a complex repeat, made up of approximately 14 GAAA tetranucleotides plus various other...
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