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Article

Mutation frequency in coding and non-coding repeat sequences in mismatch repair deficient cells derived from normal human tissue.

Oncogene - 8 Nov 2001

Bacon A L, Farrington S M, Dunlop M G

Abstract excerpt

Repetitive tracts within the coding regions of TGFBR2 and BAX are frequently mutated in mismatch repair deficient tumours and are implicated in tumour progression. However, there has been little study of the balance between selection pressure and inherent instability at sequences within these genes. To determine whether TGFBR2 and BAX are inherently prone to mutations in the presence of MMR defects, we studied...

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Share to bcl-2-Associated X Protein
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11709717
DOI: 10.1038/sj.onc.1204973

Genes

BAX
TGFBR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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