Article

The rate of spontaneous mutations in yeast deficient for MutSβ function

2022-08-26

Abstract excerpt

Mutations in simple sequence repeat loci underlie many inherited disorders in humans, and are increasingly recognized as important determinants of natural phenotypic variation. In eukaryotes, mutations in these sequences are primarily repaired by the MutSβ mismatch repair complex. To better understand the role of this complex in mismatch repair and the determinants of simple sequence repeat mutation predisposition...

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Literature Corpus work: 528cef37-cf6a-5b72-aa5f-fcd39b7a5043
DOI: 10.1101/2022.08.25.505291

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