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Article

Sequence dependent instability of mononucleotide microsatellites in cultured mismatch repair proficient and deficient mammalian cells.

Human molecular genetics - 15 Mar 2002

Boyer Jayne C, Yamada Nazumi A, Roques C Natalia, Hatch Stephanie B, Riess Kevin, Farber Rosann A

Abstract excerpt

We have measured the mutation rates of G(17) and A(17) repeat sequences in cultured mammalian cells with and without mismatch repair and have compared these rates to those of a (CA)(17) repeat sequence. Plasmids containing microsatellites that disrupt the reading frame of a downstream neomycin-resistance gene were introduced into the cells by transfection and revertants were selected using the neomycin analog...

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Identifiers

PMID: 11912186
DOI: 10.1093/hmg/11.6.707

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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