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Article

Interaction between a genetic variant of the platelet fibrinogen receptor and fibrinogen levels in determining the risk of cardiovascular events.

American heart journal - 1 Jan 2004

Boekholdt S Matthijs, Peters Ron J G, de Maat Moniek P M, Zwinderman Aeilko H, van Der Wall Ernst E, Reitsma Pieter H, Jukema J Wouter, Kastelein John J P

Abstract excerpt

BACKGROUND: The PlA1A2 polymorphism of glycoprotein IIIa (GPIIIa), which affects postoccupancy signaling by the platelet fibrinogen receptor IIbIIIa, has been investigated as a potential genetic risk factor for cardiovascular events in numerous studies, without consistent results. We investigated whether the effect of this genetic variant of the platelet fibrinogen receptor on the risk of cardiovascular events is...

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Source

Identifiers

PMID: 14691438
DOI: 10.1016/j.ahj.2003.07.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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