Article
Identification of gene-gene and gene-environment interactions within the fibrinogen gene cluster for fibrinogen levels in three ethnically diverse populations.
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2015
Jeff Janina M, Brown-Gentry Kristin, Crawford Dana C
Abstract excerpt
Elevated levels of plasma fibrinogen are associated with clot formation in the absence of inflammation or injury and is a biomarker for arterial clotting, the leading cause of cardiovascular disease. Fibrinogen levels are heritable with >50% attributed to genetic factors, however little is known about possible genetic modifiers that might explain the missing heritability. The fibrinogen gene cluster is comprised...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.