Article
Platelet glycoprotein IIb/IIIa genetic polymorphism is associated with plasma fibrinogen levels in myocardial infarction patients. The REGICOR Investigators.
Clinical biochemistry - 1 Nov 1998
Sentí M, Aubó C, Bosch M, Pavesi M, Pena A, Masiá R, Marrugat J
Abstract excerpt
Fibrinogen is the major ligand of platelet glycoprotein IIb/IIIa platelet receptor. Genes coding for platelet fibrinogen receptor glycoprotein IIb/IIIa are polymorphic. The PLA alloantigen has two antigenic determinants, PLA1 and PLA2, located in a 17-23 kD fragment of glycoprotein IIIa. We analy...
Topics
- Chi-Square Distribution
- Female
- Fibrinogen
- Genotype
- Humans
- Male
- Middle Aged
- Myocardial Infarction
- Platelet Glycoprotein GPIIb-IIIa Complex
- Polymorphism, Genetic
- Statistics as Topic