Article
Platelet glycoprotein IIb/IIIa genetic polymorphism is associated with plasma fibrinogen levels in myocardial infarction patients. The REGICOR Investigators.
Clinical biochemistry - 1 Nov 1998
Sentí M, Aubó C, Bosch M, Pavesi M, Pena A, Masiá R, Marrugat J
Abstract excerpt
Fibrinogen is the major ligand of platelet glycoprotein IIb/IIIa platelet receptor. Genes coding for platelet fibrinogen receptor glycoprotein IIb/IIIa are polymorphic. The PLA alloantigen has two antigenic determinants, PLA1 and PLA2, located in a 17-23 kD fragment of glycoprotein IIIa. We analyzed whether PLA genotype has any effect on plasma fibrinogen concentration and investigated if the effect has different...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
